Dr Charles Shepherd, Hon. Medical Adviser, ME Association.
I am currently in the process of updating the ME Association information leaflet that covers all aspects of the use of low dose amitriptyline in the management of M.E.
Amitriptyline is a long-established drug that affects brain chemical transmitter systems and was initially used to treat depression.
Can help relieve pain and provide for better sleep…
At much lower doses than used for depression, amitriptyline has been found to be helpful.
For some people it can reduce pain (muscle, joint and nerve and IBS type pain) and improve disturbed sleeping patterns.
These symptoms can occur in a wide range of medical conditions – including M.E.
…and for migraine relief.
Amitriptyline has also been used to help prevent migraine-type headaches occurring. Migraine-type headaches are more common in M.E.
The 2010 MEA Management Report indicated that some people do find it helpful for pain relief and/or sleep disturbance.
But others do not, and it can cause unpleasant side-effects. So, this is another ’try it and see’ approach to symptom management.
If you have any experience – positive or negative – of using amitriptyline for pain, sleep, or any other symptoms, please let us know using either the comments section below or via the MEA Facebook page.
The ME Association Christmas Appeal
More Research for M.E. in 2019
If you would like to support our Christmas Appeal, which aims to raise vital funds for more biomedical research in 2019, then please:
- Visit our JustGiving Page to start fundraising or to make an online donation,
- Send a cheque payable to The ME Association (with a note saying that it is for the Christmas Appeal) to ME Association, 7 Apollo Office Court, Radclive Road, Gawcott, Buckinghamshire, MK18 4DF.
- Make a donation by card over the phone to head office (01280 818964).
For more information, visit the Christmas Appeal page of our website.
ME Association Registered Charity Number 801279