Parliamentary Question | Booth, Myhill and McLaren-Howard mitochondrial dysfunction study | 17 July 2012

In a written question, the Countess of Mar asked the Government – further to the Written Answer by Earl Howe on 25 June – what assessment they have made of the findings recently published in the International Journal of Clinical and Experimental Medicine on mitochondrial dysfunction; and whether mitochondrial dysfunction occurs in any medical conditions other than chronic fatigue syndrome or myalgic encephalomyelitis.

Earl Howe, Parliamentary Under-Secretary of State at the Department for Health, replied on 17 July 2012:

We have made no assessment of this study, which looks at mitochondrial function in patients with chronic fatigue syndrome/myalgic encephalomyelitis.

Mitochondrial disease affects all organ systems and mitochondrial dysfunction has been increasingly linked with a number of neurological conditions including stroke, seizures, ataxia, migraine and Parkinson’s disease. There is also an association between mitochondrial dysfunction and a number of retinal degenerations, including diabetic retinopathy, glaucoma and age-related macular degeneration, as well as in some cardiac conditions such as cardiomyopathy or conduction defects.

The most common condition related to mitochondrial dysfunction in the endocrine system is diabetes and adult onset diabetes has been found to have a mitochondrial component.

Abstract of the study. The full text can also be downloaded.

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