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What causes ME/CFS?

What causes ME/CFS leaflet cover with a man in bed and scientific test in test tubes

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This leaflet looks at the history of ME/CFS, research into causation and Long Covid overlaps with ME/CFS. It looks at predisposing, precipitating and perpetuating factors and what we currently know and do not know about this multisystem illness, reviewing current and future research.

This leaflet is written by Dr Charles Shepherd, Trustee and Hon. Medical Adviser to The ME Association.

If you would like to print the poster included in the booklet, you can download it separately here:

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Please note

The contents of our information booklets are correct at the time of publishing. Literature is continually under review and updates are published periodically.

Medical Disclaimer : This leaflet is not intended to be a substitute for personalised medical advice or treatment. You should consult your doctor whenever a new symptom arises, or an existing symptom worsens. It is important to obtain medical advice that considers other causes and possible treatments. Do not assume that new or worsened symptoms are solely because of ME/CFS or Long Covid.

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