The information on severe ME taken from the ME Association ME/CFS/PVFS Clinical & Research Guide 2022 Edition (The ‘Purple Book') is now available to download for free.

This helpful information from Dr Charles Shepherd, MEA Honorary Medical Adviser can be used to inform healthcare professionals in primary or secondary care about the disease.

It also highlights the 2021 NICE Guideline recommendations (see 1.17) on severe ME, which is helpful for clinicians and the multidisciplinary team who may be involved in providing care for those severely affected.