Published research

We list in chronological order all the research that has been published on ME/CFS since the year 2000 that received financial support from the ME Association Ramsay Research Fund.

There are two additional pages in this section that relate to published research:

• ME Association summary research reviews,
• The PACE trial reanalysis, illness management reports and other trial reviews

Published Research (from 2000 to present):

2020: Oltra et al. Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in ME/CFS

2019: Geraghty et al. The ‘cognitive behavioural model’ of chronic fatigue syndrome: Critique of a flawed model

2019: Tomas et al. Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients using two cell types

2019: Polli, Nijs et al. Relationship Between Exercise-induced Oxidative Stress Changes and Parasympathetic Activity in Chronic Fatigue Syndrome: An Observational Study in Patients and Healthy Subjects

2018: Xu, Morten, Huang, et al. A new approach to find biomarkers in CFS/ME by single-cell Raman micro-spectroscopy

2018: Keith Geraghty & Charlotte Blease ME/CFS and the biopsychosocial model: a review of patient harm and distress in the medical encounter

2017: Tomas et al. Cellular bioenergetics is impaired in patients with chronic fatigue syndrome

2017: Keith Geraghty et al. ME/CFS patients’ reports of symptom changes following cognitive behavioural therapy, graded exercise therapy and pacing treatments: Analysis of a primary survey compared with secondary surveys

2017: Jo Nijs et al. The Role of Autonomic Function in Exercise-induced Endogenous Analgesia: A Case-control Study in ME/CFS and Healthy People

2017: Joanna Elson et al. Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome (The MEA contributed £5,000 to this study which was largely funded by Action for M.E.)

2015: Anne McArdle et al. The Role of Cytokines in Muscle Fatigue in Patients with Chronic Fatigue Syndrome (CFS)

2015: Zoe Gotts et al. The Experience of Sleep in Chronic Fatigue Syndrome: A Qualitative Interview Study with Patients

2012: Julia Newton et al. Loss of Capacity to Recover from Acidosis on Repeat Exercise in Chronic Fatigue Syndrome: A Case-control Study

2009: Derek Pheby and Lisa Saffron, Risk Factors for Severe ME/CFS

2009: John Gow et al. A Gene Signature for Post-infectious Chronic Fatigue Syndrome

2008: Rhona Wilson et al. Dietary Intervention in Chronic Fatigue Syndrome

2006: Ronald A. Chalmers et al. CFSUM1 and CFSUM2 in Urine from Patients with Chronic Fatigue Syndrome are Methodological Artefacts

2005: Mark G. Jones et al. Plasma and Urinary Carnitine and Acylcarnitines in Chronic Fatigue Syndrome

2005: Mark G. Jones et al. Urinary and Plasma Organic Acids and Amino Acids in Chronic Fatigue Syndrome

2003: Evelina Georgiades et al. Chronic Fatigue Syndrome: New Evidence for a Central Fatigue Disorder

2003: Faisel Khan et al. Prolonged Acetylcholine-induced Vasodilatation in the Peripheral Microcirculation of Patients with Chronic Fatigue Syndrome

2001: John Gow et al. Antiviral Pathway Activation in Patients with Chronic Fatigue Syndrome and Acute Infection

2000: Jonathan Brooks et al. Proton Magnetic Resonance Spectroscopy and Morphometry of the Hippocampus in Chronic Fatigue Syndrome

The ME Association

Ramsay Research Fund

We are a national charity working hard to improve the lives of people devastated by an often-misunderstood neurological disease. 

We believe biomedical research offers the best hope to people affected by M.E. If you would like to support our investment then please donate to the Ramsay Research Fund. 

Just click the image opposite to visit our JustGiving page for single donations or to establish a regular payment. You can even establish your own fundraising event.

Or why not join the ME Association as a member and be part of our growing community? For a monthly (or annual) subscription you will also receive ME Essential – quite simply the best M.E. magazine!

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ME Association Registered Charity Number 801279

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Visit the other pages in this section:

• Research Projects:
  RRF investment in infrastructure and laboratory research. Also, position statements on long-term initiatives like the Rituximab clinical trial and the Post-Mortem Tissue Bank and how you can donate tissue after death.
• Published Research:
  RRF studies from 2000 to present; PACE Trial reanalysis and critical commentary, and MEA illness management reports and critical trial reviews; MEA research summaries and research updates.
• Volunteering for Research:
  ME/CFS research requiring volunteers.
• CFS/ME Research Collaborative:
  The ME Association is an active member of the Executive Board of the CMRC. Here you can learn more about this organisation, become a member, read the conference reviews, and meeting summaries.

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