ME Association – Research Summary: The Pathology of ME

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This Free Factsheet provides a summary of what biomedical research is telling us about M.E. It considers key symptoms, common triggers, and explains how various aspects of disease pathology could be linked to specific symptoms.

Description

This Free Factsheet provides a summary of what biomedical research is telling us about M.E. It considers key symptoms, common triggers, and explains how various aspects of disease pathology could be linked to specific symptoms.

All references for the research along with more detail about these studies, can be found in the ME Association’s Clinical and Research Guide and in the research reviews that are available free in the Research section of the website.

“The most widely accepted model for M.E. is that it is a complex, multisystem disease which is triggered by an immune system stressor, commonly an infection, in a genetically predisposed individual.

“The illness is then perpetuated by interaction of various changes in the brain, muscles, immune and endocrine (hormone) systems. Until we have a better understanding of the underlying disease pathways, and the various clinical and pathological sub-groups, progress in developing a reliable diagnostic test and an effective form of drug treatment is likely to remain slow.

“However, important clues are emerging, and new types of drug treatment are being assessed on the basis of these abnormalities. And there is movement on the central
funding front with groups like the CFS/ME Research Collaborative (CMRC) working to advance the case for M.E. research investment…”

Telephone Helpline

The ME Association telephone helpline – ME Connect – is available every day of the year, during the hours of 10am-12noon, 2pm-4pm and 7pm-9pm. Please phone: 0344 576 5326 if you have any questions or would simply like to talk to someone who is there to listen.

Please note this leaflet is a download. You can read it on-screen and save to your computer, phone or other device and can attach it to any email you might need to send. But you will need access to a printer if you wish it printed.

ME CONNECT HELPLINE

0344 576 5326

Available every day of the week between these times: 10am - 12noon, 2pm - 4pm and 7pm - 9pm.

Calls cost the same as other standard landline numbers (starting 01 or 02). If you have a call package for your landline or mobile phone then calls will normally come out of your inclusive minutes.