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Questions in the Category: Intermittent Claudication

Leg pain – could it be caused by ME/CFS?

ME Essential Spring 2026

Like most people with ME/CFS, I often have muscle or nerve pain in various parts of my body – often brought on or made worse by activity. But I've recently had a more unusual and very localised pain in the calf muscles of my legs. It's not usually present at rest and normally comes on when I have been for a longish walk – which I can still manage to do. I should add that I'm in my early sixties, am a bit overweight, also have mild diabetes, and have had ME for about 15 years.

Is this very specific type of activity-induced pain in the legs being caused by ME? Or do I need to see my GP?

Charles Shepherd
ME Essential magazine
ME Medical magazine
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